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[9.21]NS Forum NO. 275-Nano-imaging revealing ultrastructural diversity of neuronal synapses
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| 2016-09-20 | 浏览次数: | 文章来源: | 【大 中 小】 |
中科院纳米生物效应与安全性重点实验室
纳米技术论坛 (NS Forum No.275)
第275期学术报告会通知
题 目：Nano-imaging revealing ultrastructural diversity of neuronal synapses
报告人：毕国强教授 中国科学技术大学
时 间：2016年9月21日 (星期三), 下午15:00
地 点：国家纳米科学中心，南楼四层会议室
主持人：王琛 研究员
报告摘要
Neuronal synapses are key communication devices in brain circuits. Within the synapse, various subcellular components form highly ordered yet dynamic structure to carry out critical functions of information transmission and storage. New microscopic techniques, including super-resolution optical imaging and cryo-electron tomography, have allowed us to visualize the inside organization of the synapse at nanometer resolution. Using these techniques, we have begun to reveal the diversity of synaptic ultrastructure and to gain insights regarding mechanisms underlying synaptic function and plasticity.
个人简介： Bi Guo-Qiang is a professor, Changjiang Scholar of School of Life Sciences at University of Science and Technology of China. He obtained a Bachelor degree in 1989 from the Department of Physics of Peking University and received his master's degree in physics in 1991 at New York University. From 1991 to 1996, he studied at the University of California, Berkeley, received a PhD in biophysics, during which he found calcium ion dependent exocytosis as a regulation mechanism for cell membrane resealing. During a postdoctoral study from 1996 to 2000 at the University of California, San Diego, he found hippocampal synaptic plasticity dependence on the precise discharge time (STDP). Since 2000 he served as assistant professor and then associate professor (tenure), adjunct associate professor in School of Medicine, at the University of Pittsburgh, and further clarify the rules for higher order STDP, its calculated properties and molecular mechanisms. In collaboration with Professor Liu Bei-Ming, he found ex vivo nerve network’s collective response activities. In 2007 he was employed by China University of Technology and founded the Neurophysics Laboratory and Nerve Photonics Workstation. Due to the outstanding contributions to the area of neuroplasticity and neural computing, he won the Burroughs Wellcome Career Award, Chancellor's Distinguished Research Award and won the National Outstanding Youth Science Foundation. He has published more than 20 papers in Science, Nature, J. Cell Biol., J. Neurosci., Nat. Neurosci., PNAS and other journals, which have been cited more than 2,000 times. |
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