姓名：李  敏
     职称：研究员
     Tel: 010-88236465 / 88236331
　  Email: limin@ihep.ac.cn
　  通讯地址：中国科学院高能物理研究所,
     北京市石景山区玉泉路19号(乙院), 100049

研究方向：
1. 界面微纳米功能结构的构筑及多组分生物化学分析； 
2. 重大疾病的早期诊断； 
3. 功能性多孔纳米材料的制备及其在生物检测方面的应用

个人情况简介：
      2008年于中国科学院化学研究所获理学博士学位。2008年-2011年在比利时鲁汶大学（Katholieke Universiteit Leuven, KUL）化学系从事博士后研究。2011年9月由中国科学院高能物理研究所“优秀人才引进计划”聘为副研究员，2021年9月晋升研究员。
       研究工作集中于可控构筑界面微纳米组装结构及多组分生物化学分析，利用纳米技术研究生命微观过程，开展肿瘤无创、早诊技术研究。在Nat. Chem, Angew. Chem. Int. Ed., J. Am. Chem. Soc., ACS Nano, Anal. Chem.等重要学术期刊发表论文50余篇。先后主持国家自然科学基金项目、科技部国家重点基础研究发展计划(973)项目子课题、中国教育部留学基金项目和中科院高能所“优秀人才引进计划”支持项目等多项。多次受邀参加国际和国内学术会议。

   
近期代表性论文：
1. Jing-Hao Fu, Zhen Zhong, Dan Xie, Yan-Jun Guo, De-Xuan Kong, Zhong-Xing Zhao, Zhen-Xia Zhao, Min Li “SERS-Active MIL-100(Fe) Sensory Array for Ultrasensitive and Multiplex Detection of VOCs”, Angew. Chem. Int. Ed., 2020, 59, 2 (Frontispiece)

2. Wenfeng Zhu, James Andell Hutchison, Mingdong Dong, Min Li “Frequency Shift Surface-Enhanced Raman Spectroscopy Sensing: An Ultrasensitive Multiplex Assay for Biomarkers in Human Health” ACS Sens. 2021, 6, 1704

3. Zhen Zhong, Min Li (Co-first author), Jinghao Fu, Yuexin Wang, Yaseen Muhammad, Sihan Li, Jiaxing Wang, Zhongxing Zhao, Zhenxia Zhao “Construction of Cu-bridged Cu2O/MIL(Fe/Cu) catalyst with enhanced interfacial contact for the synergistic photo-Fenton degradation of thiacloprid” Chem. Eng. J. 2020, 395, 125184

4. Jie Zhang, Yuhang Dong, Wenfeng Zhu, Dan Xie, Yuliang Zhao, Dayong Yang, and Min Li “Ultra-sensitive Detection of Circulating Tumor DNA of Lung Cancer via Enzymatically Amplified SERS Based Frequency Shift Assay” ACS Appl. Mater. Interfaces 2019, 11, 18145

5. Wen-Feng Zhu, Lin-Xiu Cheng, Min Li, Duo Zuo, Ning Zhang, Hong-Jun Zhuang, Dan Xie, Qing-Dao Zeng, James A Hutchison, Yu-Liang Zhao “Frequency Shift Raman-Based Sensing of Serum MicroRNAs for Early Diagnosis and Discrimination of Primary Liver Cancers” Anal. Chem. 2018, 90, 10144 (front cover)

6. Lin-Xiu Cheng, Zhi-Kun Zhang, Duo Zuo, Wen-Feng Zhu, Jie Zhang, Qing-Dao Zeng, Da-Yong Yang, Min Li, Yu-Liang Zhao “Ultrasensitive Detection of Serum MicroRNA Using Branched-DNA based SERS Platform Combining Simultaneous Detection of α-Fetoprotein for Early Diagnosis of Liver Cancer” ACS Appl. Mater. Interfaces 2018, 10, 34869

7. H. J. Zhuang, Z. Z. Wang, X. C. Zhang, J. A. Hutchison, W. F. Zhu, Z. Y. Yao, Y. L. Zhao and M. Li “A highly sensitive SERS-based platform for Zn(II) detection in cellular media” Chem. Commun. 2017, 53, 1797 (back cover)

8. B. C. Tang, J. J. Wang, J. A. Hutchison, L. Ma, N. Zhang, H. Guo, Z. B. Hu, M. Li, and Y. L. Zhao “Ultrasensitive, Multiplex Raman Frequency Shift Immunoassay of Liver Cancer Biomarkers in Physiological Media” ACS Nano 2016, 10, 871

9. S. Q. Chang, R. C. Liu, L. C. Wang, M. Li, K. Deng, Q. Y. Zheng, and Q. D. Zeng “Formation of Ordered Coronene Clusters in Template Utilizing the Structural Transformation of Hexaphenylbenzene Derivative Networks on Graphite Surface” ACS Nano 2016, 10, 342

10. Min Li, Duncan den Boer, Patrizia Iavicoli, Jinne Adisoejoso, Hiroshi Uji-i, Mark Van der Auweraer, David B. Amabilino, Johannes A. A. W. Elemans, and Steven De Feyter “Tip-Induced Chemical Manipulation of Metal Porphyrins at a Liquid/Solid Interface” J. Am. Chem. Soc. 2014, 136, 17418

11. Duncan den Boer, Min Li (co-first author), Thomas Habets, Patrizia Iavicoli, Alan E. Rowan, Roeland J. M. Nolte, Sylvia Speller, David B. Amabilino, Steven De Feyter and Johannes A. A. W. Elemans “Detection of different oxidation states of individual manganese porphyrins during their reaction with oxygen at a solid/liquid interface” Nat. Chem. 2013, 5, 621