该研究方向的主要发表论文如下:
1. Ge, C. C.; Du, J. F.; Zhao, L. N.; Wang, L. M.; Liu, Y.; Li, D. H.; Yang, Y. L.; Zhou, R. H.; Zhao, Y. L.; Chai, Z. F.; Chen, C. Y., Binding of blood proteins to carbon nanotubes reduces cytotoxicity. PNAS 2011, 108(41 ), 16968-16973.
2. Li, Y. Y.; Zhou, Y. L.; Wang, H. Y.; Perrett, S.; Zhao, Y. L.; Tang, Z. Y.; Nie, G. J., Chirality of Glutathione Surface Coating Affects the Cytotoxicity of Quantum Dots. Angewandte Chemie International Edition 2011, 50 (26), 5860-5864.
3. Zhu, M. T.; Wang, B.; Wang, Y.; Yuan, L.; Wang, H. J.; Wang, M.; Ouyang, H.; Chai, Z. F.; Feng, W. Y.; Zhao, Y. L., Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis. Toxicology Letters 2011 203 (2), 162-171.
4. Zhang, L.; Bai, R.; Li, B.; Ge, C.; Du, J.; Liu, Y.; Le Guyader, L.; Zhao, Y.; Wu, Y.; He, S.; Ma, Y.; Chen, C., Rutile TiO(2) particles exert size and surface coating dependent retention and lesions on the murine brain. Toxicology Letters 2011, 207 (1), 73-81.
5. Wang, Y.; Wang, B.; Zhu, M. T.; Li, M.; Wang, H. J.; Wang, M.; Ouyang, H.; Chai, Z. F.; Feng, W. Y.; Zhao, Y. L., Microglial activation, recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticle exposure. Toxicology Letters 2011, 205, 26-37.
6. He, X.; Kuang, Y. S.; Li, Y. Y.; Zhang, H. F.; Ma, Y. H.; Bai, W.; Zhang, Z. Y.; Wu, Z. Q.; Zhao, Y. L.; Chai, Z. F., Changing exposure media can reverse the cytotoxicity of ceria nanoparticles for Escherichia coli. Nanotoxicology 2011 DOI:10.3109/17435390.2011.569097.
7. Zhao, F.; Zhao, Y.; Liu, Y.; Chang, X. L.; Chen, C. Y.; Zhao, Y. L., Cellular Uptake, Intracellular Trafficking and Cytotoxicity of Nanomaterials. Small 2011, 7 (10), 1322-1337
8. Zhang, Z. Y.; Zhao, Y. L.; Chai, Z. F., Nuclear analytical techniques for nanotoxicology studies. Proc. Radiochim. Acta 2011, 1, 345-348.
9. Yan, L.; Zhao, F.; Li, S. F.; Hu, Z. B.; Zhao, Y. L., Low-toxic and safe nanomaterials by surface-chemical design, carbon nanotubes, fullerenes, metallofullerenes, and graphenes. Nanoscale 2011, 3 (2), 362-382.
10. Ma, Y. H.; He, X.; Zhang, P.; Zhang, Z. Y.; Guo, Z.; Tai, R. Z.; Xu, Z. J.; Zhang, L. J.; Ding, Y. Y.; Zhao, Y. L.; Chai, Z. F., Phytotoxicity and biotransformation of La2O3 nanoparticles in a terrestrial plant cucumber (Cucumis sativus). Nanotoxicology 2011,5 (4), 743-753.
11. Ge, C. C.; Meng, L.; Xu, L. G.; Bai, R.; Du, J. F.; Zhang, L.; Li, Y.; Chang, Y. Z.; Zhao, Y. L.; Chen, C. Y., Acute pulmonary and moderate cardiovascular responses of spontaneously hypertensive rats after exposure to single-wall carbon nanotubes. Nanotoxicology 2011, doi:10.3109/17435390.2011.587905.
12. Feng, W. Y.; Wang, M.; Guan, M.; Hui, Y.; Shi, J. W.; Wang, B.; Zhu, M. T.; Ouyang, H.; Zhao, Y. L.; Chai, Z. F., Mercury speciation and mercury-binding protein study by HPLC-ICP-MS on the estimation of mercury toxicity between maternal and infant rats. J. Anal. At. Spectrom. 2011, 26 (1), 156-164.
13. Zhao, Y. L., Crossroads of nanosafety and their biological effects. Toxicology Letters 2010, 196 S4-S5.
14. Zhang, H. F.; He, X.; Bai, W.; Guo, X. M.; Zhang, Z. Y.; Chai, Z. F.; Zhao, Y. L., Ecotoxicological assessment of lanthanum with Caenorhabditis elegans in liquid medium. Metallomics 2010, 2 (12), 806 - 810.
15. Yang, S. T.; Liu, J. H.; Wang, J.; Yuan, Y.; Cao, A. N.; Wang, H. F.; Liu, Y. F.; Zhao, Y. L., Cytotoxicity of Zinc Oxide Nanoparticles: Importance of Microenvironment. Journal of Nanoscience and Nanotechnology 2010, 10 (12), 8638-8645.
16. Wang, B.; Wang, Z.; Feng, W. Y.; Wang, M.; Hu, Z. B.; Chai, Z. F.; Zhao, Y. L., New methods for nanotoxicology: synchrotron radiation-based techniques. Analytical and Bioanalytical Chemistry 2010, 398, 667-676.
17. Ma, Y. H.; Kuang, L. L.; He, X.; Bai, W.; Ding, Y. Y.; Zhang, Z. Y.; Zhao, Y. L.; Chai, Z. F., Effects of rare earth oxide nanoparticles on root elongation of plants. Chemosphere 2010, 78 (3), 273-279.
18. He, X.; Zhang, H. F.; Ma, Y. H.; Bai, W.; Zhang, Z. Y.; Lu, K.; Ding, Y. Y.; Zhao, Y. L.; Chai, Z. F., Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation. Nanotechnology 2010, 21 (28), 285103 (8pp).
19. Bai, W.; Zhang, Z. Y.; Tian, W. J.; He, X.; Ma, Y. H.; Zhao, Y. L.; Chai, Z. F., Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism. Journal of Nanoparticle Research 2010, 12 (5), 1645-1654.
20. Zhu, M. T.; Feng, W. Y.; Wang, Y.; Wang, B.; Wang, M.; Ouyang, H.; Zhao, Y. L.; Chai, Z. F., Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicological Sciences 2009, 107 (2), 342-351.
21. Zhang, Z. Y.; Zhao, Y. L.; Chai, Z. F., Applications of radiotracer techniques for the pharmacology and toxicology studies of nanomaterials. Chinese Science Bulletin 2009, 54 (2), 173-182.
22. Wang, B.; Feng, W. Y.; Zhu, M. T.; Wang, Y.; Wang, M.; Gu, Y. Q.; Ouyang, H.; Wang, H. J.; Li, M.; Zhao, Y. L.; Chai, Z. F.; Wang, H. F., Neurotoxicity of low-dose repeatedly intranasal instillation of nano- and submicron-sized ferric oxide particles in mice. Journal of Nanoparticle Research 2009, 11 (1), 41-53.
23. Lao, F.; Li, W.; Han, D.; Qu, Y.; Liu, Y.; Zhao, Y. L.; Chen, C. Y., Fullerene derivatives protect endothelial cells against NO-induced damage. Nanotechnology 2009, 20 (22), 225103(9pp).
24. Zhu, M. T.; Feng, W. Y.; Wang, B.; Wang, T. C.; Gu, Y. Q.; Wang, M.; Wang, Y.; Ouyang, H.; Zhao, Y. L.; Chai, Z. F., Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats. Toxicology 2008, 247 (2-3), 102-111.
25. Zhao, Y. L.; Xing, G. M.; Chai, Z. F., Nanotoxicology: Are Carbon Nanotubes Safe? Nature Nanotechnology 2008, 3 (4), 191-192.
26. Wang, J. X.; Liu, Y.; Jiao, F.; Lao, F.; Li, W.; Gu, Y. Q.; Li, Y. F.; Ge, C. C.; Zhou, G. Q.; Li, B.; Zhao, Y. L.; Chai, Z. F.; Chen, C. Y., Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles. Toxicology 2008, 254 (1-2), 82-90.
27. Wang, J. X.; Chen, C. Y.; Liu, Y.; Jiao, F.; Li, W.; Lao, F.; Li, Y. F.; Li, B.; Ge, C. C.; Zhou, G. Q.; Gao, Y.; Zhao, Y. L.; Chai, Z. F., Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases. Toxicology Letters 2008, 183 (1-3), 72-80.
28. Wang, J.; Deng, X. Y.; Yang, S. T.; Wang, H. F.; Zhao, Y. L.; Liu, Y. F., Rapid translocation and pharmacokinetics of hydroxylated single-walled carbon nanotubes in mice. Nanotoxicology 2008, 2 (1), 28-32.
29. Wang, B.; Feng, W. Y.; Wang, M.; Wang, T. C.; Gu, Y. Q.; Zhu, M. T.; Ouyang, H.; Shi, J. W.; Zhang, F.; Zhao, Y. L.; Chai, Z. F.; Wang, H. F.; Wang, J., Acute toxicological impact of nano- and submicro-scaled zinc oxide powder on healthy adult mice. Journal of Nanoparticle Research 2008, 10 (2), 263-276.
30. He, X.; Zhang, Z. Y.; Zhang, H. F.; Zhao, Y. L.; Chai, Z. F., Neurotoxicological evaluation of long-term lanthanum chloride exposure in rats. Toxicological Sciences 2008, 103 (2), 354-361.
31. Chen, Z.; Meng, H.; Xing, G. M.; Yuan, H.; Zhao, F.; Liu, R.; Chang, X. L.; Gao, X. Y.; Wang, T. C.; Jia, G.; Ye, C.; Chai, Z. F.; Zhao, Y. L., Age-related differences in pulmonary and cardiovascular responses to SiO2 nanoparticle inhalation: Nanotoxicity shows susceptible population. Environmental Science & Technology 2008, 42 (23), 8985-8992.
32. Chen, Z.; Chen, H.; Meng, H.; Xing, G. M.; Gao, X. Y.; Sun, B. Y.; Shi, X. L.; Yuan, H.; Zhang, C. C.; Liu, R.; Zhao, F.; Zhao, Y. L.; Fang, X. H., Bio-distribution and metabolic paths of silica coated CdSeS quantum dots. Toxicology and Applied Pharmacology 2008, 230 (3), 364-371.
33. Wang, J. X.; Zhou, G. Q.; Chen, C. Y.; Yu, H. W.; Wang, T. C.; Ma, Y. M.; Jia, G.; Gao, Y. X.; Li, B.; Sun, J.; Li, Y. F.; Jiao, F.; Zhao, Y. L.; Chai, Z. F., Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicology Letters 2007, 168 (2), 176-185.
34. Meng, H.; Chen, Z.; Xing, G. M.; Yuan, H.; Chen, C. Y.; Zhao, F.; Zhang, C. C.; Zhao, Y. L., Ultrahigh reactivity provokes nanotoxicity: Explanation of oral toxicity of nano-copper particles. Toxicology Letters 2007, 175 (1-3), 102-110.
35. Meng, H.; Chen, Z.; Xing, G. M.; Yuan, H.; Chen, C. Y.; Zhao, F.; Zhang, C. C.; Wang, Y.; Zhao, Y. L., Ultrahigh Reactivity and Grave Nanotoxicity of Copper Nanoparticles. Journal of Radioanalytical and Nuclear Chemistry 2007, 272 (3), 595-598.
36. He, X.; Feng, L. X.; Xiao, H. Q.; Li, Z.; Liu, N. Q.; Zhao, Y. L.; Zhang, Z. Y.; Chai, Z. F., Unambiguous effects of lanthanum? Toxicology Letters 2007, 170 (1), 94-96.
37. Chen, Z.; Meng, H.; Xing, G. M.; Chen, C. Y.; Zhao, Y. L., Toxicological and biological effects of nanomaterials. International Journal of Nanotechnology 2007, 4 (1/2), 179-196.
38. Wang, B.; Feng, W. Y.; Wang, T. C.; Jia, G.; Wang, M.; Shi, J. W.; Zhang, F.; Zhao, Y. L.; Chai, Z. F., Acute toxicity of nano- and micro-scale zinc powder in healthy adult mice. Toxicology Letters 2006, 161 (2), 115-123.
39. Feng, L. X.; Xiao, H. Q.; He, X.; Li, Z. J.; Li, F. L.; Liu, N. Q.; Zhao, Y. L.; Huang, Y. Y.; Zhang, Z. Y.; Chai, Z. F., Neurotoxicological consequence of long-term exposure to lanthanum. Toxicology Letters 2006, 165 (2), 112-120.
40. Feng, L. X.; Xiao, H. Q.; He, X.; Li, Z. J.; Li, F. L.; Liu, N. Q.; Chai, Z. F.; Zhao, Y. L.; Zhang, Z. Y., Long-term effects of lanthanum intake on the neurobehavioral development of the rat. Neurotoxicol. Teratol. 2006, 28 (1), 119-124.
41. Chen, Z.; Meng, H.; Xing, G. M.; Chen, C. Y.; Zhao, Y. L.; Jia, G. A.; Wang, T. C.; Yuan, H.; Ye, C.; Zhao, F.; Chai, Z. F.; Zhu, C. F.; Fang, X. H.; Ma, B. C.; Wan, L. J., Acute toxicological effects of copper nanoparticles in vivo. Toxicology Letters 2006, 163 (2), 109-120.
42. Wang, B.; Feng, W. Y.; Zhao, Y. L.; Xing, G. M.; Chai, Z. F.; Wang, H. F.; Jia, G., Status of study on biological and toxicological effects of nanoscale materials. Science in China Series B-Chemistry 2005, 48 (5), 385-394.
43. Jia, G.; Wang, H. F.; Yan, L.; Wang, X.; Pei, R. J.; Yan, T.; Zhao, Y. L.; Guo, X. B., Cytotoxicity of carbon nanomaterials: Single-wall nanotube, multi-wall nanotube, and fullerene. Environmental Science & Technology 2005, 39 (5), 1378-1383.
44. Chen, C. Y.; Xing, G. M.; Wang, J. X.; Zhao, Y. L.; Li, B.; Tang, J.; Jia, G.; Wang, T. C.; Sun, J.; Xing, L.; Yuan, H.; Gao, Y. X.; Meng, H.; Chen, Z.; Zhao, F.; Chai, Z. F.; Fang, X. H., Multi hydroxylated [Gd@C82(OH)22]n nanoparticles: Antineoplastic activity of high efficiency and low toxicity. Nano Letters 2005, 5 (10), 2050-2057.